Can clinical practice guidelines lead astray?

Circumstances When Arterial Blood Gas Analysis Can Lead Us Astray.

In this issue of RESPIRATORY CARE, Van de Louw et al1 describe the magnitude of spurious hypoxemia as suggested by arterial blood gases (ABGs) obtained from subjects with acute leukemia and hyperleukocytosis. Spurious hypoxemia, commonly known as leukocyte larceny, is just one of several erroneous values or discrepancies with pulse oximetry and the bedside assessment (or bioassay) that may occu...

Can we trust cardiovascular practice guidelines?: comment on "Conflicts of interest in cardiovascular clinical practice guidelines".

BACKGROUND Clinical practice guidelines (CPGs) serve as standards of care in practice, quality improvement, and reimbursement. The extent of conflicts of interest (COIs) in cardiology guideline production has not been well studied. Herein, we describe the scope of COIs in CPGs. METHODS We examined the 17 most recent American College of Cardiology/American Heart Association guidelines through ...

Clinical Practice Guidelines EASL Clinical Practice Guidelines: Wilson’s disease

This Clinical Practice Guideline (CPG) has been developed to assist physicians and other healthcare providers in the diagnosis and management of patients with Wilson’s disease. The goal is to describe a number of generally accepted approaches for diagnosis, prevention, and treatment of Wilson’s disease. Recommendations are based on a systematic literature review in the Medline (PubMed version),...

NHG Clinical Practice Guidelines NHG Clinical Practice Guidelines

Clinical Practice Guidelines: Principles for Clinical Practice

S5 print and electronic media where they come across lay guidelines; doctors need to inform the patients regarding available treatment alternatives, their potential harms and benefits, where clinical guidelines work as the best available educative tool. CPGs highlight gaps in known literature where treatment recommendations are not clear cut; hence it helps in identifying areas where future res...